Cheminformatic Tools and Databases for Pharmacology

session 6952 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ETHAMBUTOL

ETHAMBUTOL


ATC J04AK02
ATC J04AM03
ATC J04AM07
ATC J04AM06

ANTIINFECTIVES
ANTIBACTERIAL
TUBERCULOSTATIC
ANTIFUNGAL
ANTIBIOTIC
INHIBITS THE BIOSYNTHESIS OF CELL WALL ARABINOGALACTAN (AG) RESULTING IN ACCUMULATION OF MYCOLIC ACIDS AND CELL DEATH (PMID25547657)

ORAL

Cmax 17.1 MICROMOLAR

Tmax 3 HOUR

VD 110.5 LITER (65 KILOGRAM)

PPB 82 PERCENT

Cl 39 LITER / HOUR (65 KILOGRAM)

HT 3.1 HOUR

ARABINOSYLTRANSFERASES (PMID19596878)

PDB 5NR3 (HUMAN DNMT3B PWWP DOMAIN IN COMPLEX WITH ETHAMBUTOL)

LIGAND CODE = 95E (link to the list of PDB complexes)

Download experimental 3D coordinates of 95E with added hydrogens

ARABINOSYLTRANSFERASE A INHIBITOR CHEMBL1877 ARABINOSYLTRANSFERASE A P9WNL9 PROBABLE ARABINOSYLTRANSFERASE A MYCOBACTERIUM TUBERCULOSIS ENZYME TRANSFERASEANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |