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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLOMIPHENE

CLOMIPHENE


ATC G03GB02

GENITO
INITIATION OF OVULATION
FERTILITY AGENTS, FEMALE
ESTROGEN RECEPTOR ANTAGONIST
ZUCLOMIPHENE (CIS) HAS A LONGER HALF-LIFE THAN ENCLOMIPHENE (TRANS)

ORAL

Cmax 17 NANOMOLAR (PMID18621671)

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

ESTROGEN RECEPTOR

ESTROGEN RECEPTOR ALPHA MODULATOR CHEMBL206 ESTROGEN RECEPTOR ALPHA P03372 ESTROGEN RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3A NR3A1ANSM (in French)

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