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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TESTOLACTONE DISCONTINUED

TESTOLACTONE

ANTINEOPLASTIC
INHIBITION OF STEROID AROMATASE ACTIVITY AND CONSEQUENT REDUCTION IN ESTRONE SYNTHESIS FROM ADRENAL ANDROSTENEDIONE
TREATMENT OF BREAST CANCER IN POSTMENOPAUSAL WOMEN

ORAL INJECTION

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

CYTOCHROME P450 19 (AROMATASE)

CYTOCHROME P450 19A1 INHIBITOR CHEMBL1978 CYTOCHROME P450 19A1 P11511 AROMATASE HOMO SAPIENS ENZYME CYTOCHROME P450 CYP_19 CYP_19A CYP_19A1ANSM (in French)

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