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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMINOCAPROIC ACID
| AMINOCAPROIC ACID | BLOOD | ORAL INJECTION | Cmax 1.25 MILLIMOLAR Tmax 1.2 HOUR F 100 PERCENT VD 23.1 LITER PPB 8 PERCENT Cl 10.1 LITER / HOUR HT 2 HOUR SOLUBILITY SOLUBLE IN WATER | PLASMINOGEN PDB 2ZM9 (STRUCTURE OF 6-AMINOHEXANOATE-DIMER HYDROLASE, A61V, S112A, A124V, R187S, F264C, G291R, G338A, D370Y MUTANT (HYB-S4M94) WITH SUBSTRATE) LIGAND CODE = ACA (link to the list of PDB complexes) Download experimental 3D coordinates of ACA with added hydrogens | Plasminogen UNIPROT P00747 PLG -- Tissue-type plasminogen activator UNIPROT P00750 PLAT more at DrugCentral | EMA | |||
