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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MELPHALAN (is an active metabolite)

MELPHALAN


ATC L01AA03

ANTINEOPLASTIC
ALKYLATING
MYELOABLATIVE AGONISTS

ORAL INJECTION INTRAVENOUS

Cmax 695 NANOMOLAR

Tmax 1 HOUR

F 74 PERCENT

VD 32.5 LITER (65 KILOGRAM)

PPB 72 PERCENT

Cl 27.3 LITER / HOUR (65 KILOGRAM)

HT 1.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

DNA

DNA INHIBITOR CHEMBL2311221 DNA HOMO SAPIENSANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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