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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NALIDIXIC ACID DISCONTINUED (has an active metabolite)

NALIDIXIC ACID


ATC J01MB02

ANTIINFECTIVES
ANTIBIOTIC
GRAM-NEGATIVE BACTERIA
QUINOLONE ANTIBACTERIAL AGENT
NUCLEIC ACID SYNTHESIS INHIBITORS

ORAL

Cmax 129.3 MICROMOLAR

Tmax 1.5 HOUR

PPB 90 PERCENT

HT 6 HOUR

DNA GYRASE

BACTERIAL DNA GYRASE INHIBITOR CHEMBL2311224 BACTERIAL DNA GYRASE P0AES4 DNA GYRASE SUBUNIT A BACTERIA ENZYME ISOMERASEANSM (in French)

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ChEMBL
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