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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SILODOSIN

SILODOSIN


ATC G04CA04

GENITO
ALPHA-1 ADRENERGIC RECEPTOR ANTAGONIST
PROSTATIC HYPERPLASIA

ORAL

Cmax 124.4 NANOMOLAR

Tmax 2.6 HOUR

F 32 PERCENT

VD 49.5 LITER

PPB 97 PERCENT

Cl 10 LITER / HOUR

HT 13.3 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

ALPHA-1 ADRENERGIC RECEPTOR

ALPHA-1A ADRENERGIC RECEPTOR ANTAGONIST CHEMBL229 ALPHA-1A ADRENERGIC RECEPTOR P35348 ALPHA-1A ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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