Cheminformatic Tools and Databases for Pharmacology

session 2861 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AMITRIPTYLINE

AMITRIPTYLINE


ATC N06AA09
ATC N06CA01

NERVOUS SYSTEM
ANTIDEPRESSANT
NOREPINEPHRINE REUPTAKE INHIBITORS

ORAL INJECTION

VD 565.5 LITER (65 KILOGRAM)

PPB 93 PERCENT

Cl 23.7 LITER / HOUR (65 KILOGRAM)

HT 17 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

NORADRENALINE TRANSPORTER

PDB 3APV (CRYSTAL STRUCTURE OF THE A VARIANT OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND AMITRIPTYLINE COMPLEX)

LIGAND CODE = TP0 (link to the list of PDB complexes)

Download experimental 3D coordinates of TP0 with added hydrogens

NOREPINEPHRINE TRANSPORTER INHIBITOR CHEMBL222 NOREPINEPHRINE TRANSPORTER P23975 SODIUM-DEPENDENT NORADRENALINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |