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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VINBLASTINE
| VINBLASTINE | ANTINEOPLASTIC | INJECTION | VD 1820 LITER (65 KILOGRAM) PPB 86 PERCENT Cl 12 LITER / HOUR (65 KILOGRAM) HT 67 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | TUBULIN PDB 4EB6 (TUBULIN-VINBLASTINE: STATHMIN-LIKE COMPLEX) LIGAND CODE = VLB (link to the list of PDB complexes) Download experimental 3D coordinates of VLB with added hydrogens | Tubulin beta UNIPROT P07437 TUBB more at DrugCentral | EMA | |||
