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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CYPROHEPTADINE
| CYPROHEPTADINE | RESPIRATORY SYSTEM | ORAL | Tmax 7.5 HOUR HT 12.5 HOUR SOLUBILITY SOLUBLE IN WATER | HISTAMINE H1 RECEPTOR 5-HYDROXYTRYPTAMINE 2A RECEPTOR PDB 5AYF (CRYSTAL STRUCTURE OF SET7, 9 IN COMPLEX WITH CYPROHEPTADINE) LIGAND CODE = C7H (link to the list of PDB complexes) Download experimental 3D coordinates of C7H with added hydrogens | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
