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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OXYPHENBUTAZONE DISCONTINUED
| OXYPHENBUTAZONE |
MUSCULO-SKELETAL | ORAL | PDB 1Q7A (CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN RUSSELL'S VIPER PHOSPHOLIPASE A2 AND AN ANTIINFLAMMATORY AGENT OXYPHENBUTAZONE AT 1.6A RESOLUTION) LIGAND CODE = OPB (link to the list of PDB complexes) Download experimental 3D coordinates of OPB with added hydrogens | Cyclooxygenase UNIPROT P23219 PTGS1 more at DrugCentral | EMA | ||||
