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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DIFENOXIN (is an active metabolite)
| DIFENOXIN | METABOLISM | ORAL | Cmax 377 NANOMOLAR Tmax 0.83 HOUR HT 13 HOUR | MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DIPHENOXYLATE (has an active metabolite)
| DIPHENOXYLATE | METABOLISM | ORAL | F 90 PERCENT | MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
