Cheminformatic Tools and Databases for Pharmacology

session 67166 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TRANYLCYPROMINE

TRANYLCYPROMINE


ATC N06AF04

NERVOUS SYSTEM
ANTIDEPRESSANT
ANTI-ANXIETY AGENTS
MONOAMINE OXIDASE (MAO) INHIBITORS

ORAL

Cmax 368.4 NANOMOLAR (PMID12959316)

Tmax 1 HOUR (PMID3757407)

VD 144.5 LITER (EQN)

Cl 63.4 LITER / HOUR

HT 1.58 HOUR

MONOAMINE OXIDASE MAO

PDB 3MDR (TRANYLCYPROMINE COMPLEX OF CYTOCHROME P450 46A1)

LIGAND CODE = GJZ (link to the list of PDB complexes)

Download experimental 3D coordinates of GJZ with added hydrogens

Amine oxidase flavin-containing B UNIPROT P27338 MAOB

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |