Cheminformatic Tools and Databases for Pharmacology

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEXTROTHYROXINE DISCONTINUED

DEXTROTHYROXINE


ATC C10AX01

CARDIOVASCULAR
ANTIHYPERLIPIDEMICS

ORAL

PDB 5CR1 (CRYSTAL STRUCTURE OF TTR, RESVERATROL, T4 COMPLEX)

LIGAND CODE = T44 (link to the list of PDB complexes)

Download experimental 3D coordinates of T44 with added hydrogens

Thyroid hormone receptor UNIPROT P10827 THRA

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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