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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DEXTROTHYROXINE DISCONTINUED
| DEXTROTHYROXINE | CARDIOVASCULAR | ORAL | PDB 5CR1 (CRYSTAL STRUCTURE OF TTR, RESVERATROL, T4 COMPLEX) LIGAND CODE = T44 (link to the list of PDB complexes) Download experimental 3D coordinates of T44 with added hydrogens | Thyroid hormone receptor UNIPROT P10827 THRA more at DrugCentral | EMA | ||||
