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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ISOSORBIDE MONONITRATE

ISOSORBIDE MONONITRATE


ATC C01DA14

CARDIOVASCULAR
VASODILATOR FROM THE RELEASE OF NITRIC OXIDE

ORAL

Cmax 6.5 MICROMOLAR (60 MILLIGRAM)

F 100 PERCENT

VD 42.2 LITER

PPB 0 PERCENT

Cl 7 LITER / HOUR

HT 5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

SOLUBLE GUANYLATE CYCLASE ACTIVATOR CHEMBL2111348 SOLUBLE GUANYLATE CYCLASE O75343 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HOMO SAPIENS ENZYME LYASE GUANYLATE CYCLASE SOLUBLE GUANYLATE CYCLASEANSM (in French)

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