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session 94469 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CARISOPRODOL (has an active metabolite)

CARISOPRODOL


ATC M03BA02
ATC M03BA52
ATC M03BA72

MUSCULO-SKELETAL
MUSCLE RELAXANTS
RELIEVING DISCOMFORT ASSOCIATED WITH CUTE PAINFUL MUSCULOSKELETAL CONDITIONS
ALLOSTERIC EFFECTS ON GABA(A) RECEPTOR (PMID25896767)

ORAL

Cmax 6.92 MICROMOLAR

Tmax 1.7 HOUR

HT 2 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT ALPHA-1 (GABAA)

Unknown - more at DrugCentralANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MEPROBAMATE (is an active metabolite)

MEPROBAMATE


ATC N05BC01
ATC N05BC51
ATC N05CX01

NERVOUS SYSTEM
ANXIOLYTIC
SEDATIVE
GABA MODULATOR

ORAL

Cmax 11.4 MICROMOLAR

Tmax 4.5 HOUR

VD 45.5 LITER (65 KILOGRAM)

PPB 0 PERCENT

Cl 2.34 LITER / HOUR (65 KILOGRAM)

HT 9.6 HOUR

GAMMA-AMINOBUTYRIC-ACID RECEPTOR (GABA) (PMID9067327)

GABA-A RECEPTOR ANION CHANNEL AGONIST CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P14867 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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