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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
THIOTEPA

THIOTEPA


ATC L01AC01

ANTINEOPLASTIC
ALKYLATING AGENT OF DNA

INJECTION INTRACAVITARY INTRAVENOUS INTRAVESICAL

Cmax 10.3 MICROMOLAR

VD 104 LITER (65 KILOGRAM)

PPB 10 PERCENT

Cl 25.14 LITER / HOUR

HT 2.4 HOUR

DNA

Unknown

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