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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
METHOHEXITAL

METHOHEXITAL


ATC N01AF01
ATC N05CA15

NERVOUS SYSTEM
HYPNOTIC
ANXIOLYTIC
ANESTHETIC
BARBITURATES
GABA ALLOSTERIC MODULATOR

INJECTION

Cmax 30 MICROMOLAR

VD 71.5 LITER (65 KILOGRAM)

PPB 73 PERCENT

Cl 46 LITER / HOUR (65 KILOGRAM)

HT 1.6 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT ALPHA-1

GABA-A RECEPTOR ANION CHANNEL POSITIVE ALLOSTERIC MODULATOR CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P18505 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

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