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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DICHLORPHENAMIDE
| DICHLORPHENAMIDE | SENSORY | ORAL | CARBONIC ANHYDRASE PDB 2POU (THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4,5-DICHLORO-BENZENE-1,3-DISULFONAMIDE) LIGAND CODE = I7A (link to the list of PDB complexes) Download experimental 3D coordinates of I7A with added hydrogens | Carbonic anhydrase 2 UNIPROT P00918 CA2 -- Carbonic anhydrase 1 UNIPROT P00915 CA1 more at DrugCentral | EMA | ||||
