| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HALOTHANE DISCONTINUED
| HALOTHANE | NERVOUS SYSTEM | INHALATION | POLYPHARMACOLOGY (VOLTAGE-DEPENDENT ANION CHANNEL, GABA, PMID24563623) PDB 2JST (FOUR-ALPHA-HELIX BUNDLE WITH DESIGNED ANESTHETIC BINDING POCKETS II: HALOTHANE EFFECTS ON STRUCTURE AND DYNAMICS) LIGAND CODE = HLT (link to the list of PDB complexes) Download experimental 3D coordinates of HLT with added hydrogens | Potassium channel subfamily K member 2 UNIPROT O95069 KCNK2 -- Potassium channel subfamily K member 3 UNIPROT O14649 KCNK3 more at DrugCentral | EMA | ||||
