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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CHLORZOXAZONE

CHLORZOXAZONE


ATC M03BB03
ATC M03BB53
ATC M03BB73

MUSCULO-SKELETAL
MUSCLE RELAXANT
SEDATIVES

ORAL

Tmax 1.5 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

NITRIC OXIDE SYNTHASE (NOS) OXYGENASE

PDB 1M9J (HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE WITH CHLORZOXAZONE BOUND)

LIGAND CODE = CLW (link to the list of PDB complexes)

Download experimental 3D coordinates of CLW with added hydrogens

INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 OPENER CHEMBL4305 INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 O15554 INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 HOMO SAPIENS ION CHANNEL VGC K CA ACT KANSM (in French)

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