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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DICUMAROL DISCONTINUED
| DICUMAROL | BLOOD | ORAL | HT 16.5 HOUR | XANTHINE OXIDASE (XO) XANTHINE DEHYDROGENASE (XDH) (PMID1281039) | VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 ISOFORM 1 INHIBITOR CHEMBL1930 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 ISOFORM 1 Q9BQB6 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 HOMO SAPIENS ENZYME REDUCTASE | ANSM (in French) | |||
