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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEXTROMETHORPHAN

DEXTROMETHORPHAN


ATC N06AX62
ATC R05DA09
ATC N07XX59

NERVOUS SYSTEM
ANTITUSSIVE
UNCOMPETITIVE GLUTAMATE [NMDA] RECEPTOR ANTAGONIST
SIGMA 1-TYPE RECEPTOR AGONIST
TREATMENT OF PSEUDOBULBAR AFFECT (PBA)
SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR

ORAL

Tmax 3.5 HOUR

PPB 65 PERCENT

HT 13 HOUR

SIGMA 1-TYPE OPIOID RECEPTOR
GLUTAMATE [NMDA] RECEPTOR

Unknown

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