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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHYLPREDNISOLONE (is an active metabolite)
| METHYLPREDNISOLONE |
DERMATOLOGICALS | ORAL OPHTHALMIC | VD 78 LITER (65 KILOGRAM) PPB 77 PERCENT Cl 23.8 LITER / HOUR (65 KILOGRAM) HT 2.3 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
