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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CHLOROTHIAZIDE

CHLOROTHIAZIDE


ATC C03AA04
ATC C03AB04
ATC C03AH01

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
MAY INVOLVE CARBONIC ANHYDRASE INHIBITION (PMID24352504)

ORAL INJECTION

HT 2 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

CARBONIC ANHYDRASE

THIAZIDE-SENSITIVE SODIUM-CHLORIDE COTRANSPORTER INHIBITOR CHEMBL1876 THIAZIDE-SENSITIVE SODIUM-CHLORIDE COTRANSPORTER P55017 SOLUTE CARRIER FAMILY 12 MEMBER 3 HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC12ANSM (in French)

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