| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GUAIFENESIN (is an active metabolite)
| GUAIFENESIN | RESPIRATORY SYSTEM | ORAL | Cmax 18.6 MICROMOLAR Tmax 0.33 HOUR HT 1 HOUR SOLUBILITY 1 GRAM IN 20 MILLILITER IN WATER | Unknown more at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GUAIFENESIN (is an active metabolite)
| GUAIFENESIN | RESPIRATORY SYSTEM | ORAL | Unknown more at DrugCentral | EMA | |||||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHOCARBAMOL (has an active metabolite)
| METHOCARBAMOL |
MUSCULO-SKELETAL SYSTEM | ORAL IM INJECTION | Cmax 96 MICROMOLAR VD 150 LITER (EQN) PPB 50 PERCENT Cl 52 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | Carbonic anhydrase 1 UNIPROT P00915 CA1 more at DrugCentral | EMA | ||||
| 4 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHOCARBAMOL (has an active metabolite)
| METHOCARBAMOL |
MUSCULO-SKELETAL SYSTEM | ORAL IM INJECTION | Cmax 96 MICROMOLAR VD 150 LITER (EQN) PPB 50 PERCENT Cl 52 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | Carbonic anhydrase 1 UNIPROT P00915 CA1 more at DrugCentral | EMA | ||||
