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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PROPOXYPHENE DISCONTINUED (has an active metabolite)

PROPOXYPHENE


ATC N02AC04
ATC N02AC54
ATC N02AC74

NERVOUS SYSTEM
ANALGESICS
OPIOID AGONIST
ANTITUSSIVES
NARCOTICS

ORAL

Cmax 0.21 MICROMOLAR (65 MILLIGRAM)

Tmax 2.25 HOUR

VD 780 LITER (65 KILOGRAM)

PPB 80 PERCENT

Cl 58.5 LITER / HOUR (65 KILOGRAM)

HT 9 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

OPIOID RECEPTOR

MU OPIOID RECEPTOR AGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTORANSM (in French)

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