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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MAVORIXAFOR

MAVORIXAFOR

BLOOD
CXC CHEMOKINE RECEPTOR 4 (CXCR4) ANTAGONIST
TREATMENT OF WHIM SYNDROME (WARTS, HYPOGAMMAGLOBULINEMIA, INFECTIONS AND MYELOKATHEXIS)

ORAL

Cmax 9.45 MICROMOLAR

Tmax 2.8 HOUR

VD 768 LITER

PPB 93 PERCENT

Cl 62 LITER / HOUR

HT 82 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN PH 7.5 AQUEOUS BUFFER

CXC CHEMOKINE RECEPTOR 4 (CXCR4)

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ChEMBL
BindingDB
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