Cheminformatic Tools and Databases for Pharmacology

session 89027 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NORETHINDRONE (is an active metabolite)

NORETHINDRONE


ATC G03AC01
ATC G03DC02
ATC G03FA01
ATC G03FB05
ATC G03AA05
ATC G03AB04

GENITO
PROGESTIN
CONTRACEPTIVES

ORAL

Cmax 87.8 NANOMOLAR

Tmax 1.83 HOUR

F 64 PERCENT

VD 260 LITER (65 KILOGRAM)

PPB 61 PERCENT

Cl 26 LITER / HOUR (65 KILOGRAM)

HT 8.51 HOUR

PROGESTERONE RECEPTOR

PDB 2W8Y (RU486 BOUND TO THE PROGESTERONE RECEPTOR IN A DESTABILIZED AGONISTIC CONFORMATION)

LIGAND CODE = NDR (link to the list of PDB complexes)

Download experimental 3D coordinates of NDR with added hydrogens

PROGESTERONE RECEPTOR AGONIST CHEMBL208 PROGESTERONE RECEPTOR P06401 PROGESTERONE RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C3ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NORETHINDRONE ACETATE (has an active metabolite)

NORETHINDRONE ACETATE


ATC G03AC01
ATC G03DC02
ATC G03FA01
ATC G03FB05
ATC G03AA05
ATC G03AB04

GENITO
PROGESTIN
CONTRACEPTIVE
RAPIDLY HYDROLYZED IN NORETHINDRONE

ORAL TRANSDERMAL INTRAMUSCULAR PROGESTERONE RECEPTOR

PROGESTERONE RECEPTOR AGONIST CHEMBL208 PROGESTERONE RECEPTOR P06401 PROGESTERONE RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C3ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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