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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ETRASIMOD

ETRASIMOD


ATC L04AE05

IMMUNOSUPPRESSANTS
IMMUNOMODULATING AGENTS
SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATOR
TREATMENT OF MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS

ORAL

Cmax 247 NANOMOLAR

Tmax 4 HOUR

VD 66 LITER

PPB 97.9 PERCENT

Cl 1 LITER / HOUR

HT 30 HOUR

SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR

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