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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FEZOLINETANT
| FEZOLINETANT | GENITO | ORAL | Tmax 1.5 HOUR VD 189 LITER PPB 51 PERCENT Cl 10.8 LITER / HOUR HT 9.6 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER (0.29 MILLIGRAM PER MILLILITER) | NEUROKININ 3 (NK3) RECEPTOR | Neuromedin-K receptor UNIPROT P29371 more at DrugCentral | EMA | |||
