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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SPARSENTAN
| SPARSENTAN | CARDIOVASCULAR | ORAL | Cmax 11.7 MICROMOLAR Tmax 3 HOUR VD 61.4 LITER PPB 99 PERCENT Cl 3.88 LITER / HOUR HT 9.6 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | ANGIOTENSIN II TYPE 1 RECEPTOR (AT1R) ENDOTHELIN TYPE A RECEPTOR (ETAR) | Type-1 angiotensin II receptor UNIPROT P30556 AGTR1 -- Endothelin-1 receptor UNIPROT P25101 EDNRA more at DrugCentral | EMA | |||
