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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ADAGRASIB
| ADAGRASIB | ANTINEOPLASTIC | ORAL | Tmax 6 HOUR VD 942 LITER PPB 98 PERCENT Cl 37 LITER / HOUR HT 23 HOUR SOLUBILITY LESS THAN 0.010 MILLIGRAM PER MILLITER AT PH 7.4 | KRAS G12C | GTPase KRas UNIPROT P01116 more at DrugCentral | EMA | |||
