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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RITLECITINIB
| RITLECITINIB | ANTINEOPLASTIC | ORAL | Tmax 1 HOUR F 64 PERCENT PPB 14 PERCENT HT 1.8 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | JANUS KINASE 3 (JAK3) | Tyrosine-protein kinase JAK3 UNIPROT P52333 more at DrugCentral | EMA | |||
