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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BEXAGLIFLOZIN

BEXAGLIFLOZIN


ATC A10BK08

METABOLISM
SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2) INHIBITOR
ANTIDIABETIC
REDUCES RENAL REABSORPTION OF FILTERED GLUCOSE
TREATMENT OF TYPE 2 DIABETES MELLITUS

ORAL

Cmax 288 NANOMOLAR

Tmax 3 HOUR

VD 262 LITER

PPB 93 PERCENT

Cl 19.1 LITER / HOUR

HT 12 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

SODIUM-GLUCOSE CO-TRANSPORTER 2
SGLT2

sodium-glucose co-transporter 2 UNIPROT P31639

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