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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ODEVIXIBAT

ODEVIXIBAT


ATC A05AX05

METABOLISM
ILEAL BILE ACID TRANSPORTER INHIBITOR (IBAT)
TREATMENT OF PRURITUS IN PATIENTS WITH PFIC

ORAL

Cmax 0.9 NANOMOLAR

Tmax 3 HOUR

PPB 99 PERCENT

HT 2.3 HOUR

SOLUBILITY INCREASES IN WATER WITH PH

ILEAL BILE ACID TRANSPORTER

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