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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FINERENONE

FINERENONE


ATC C03DA05

CARDIOVASCULAR
NON STEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONIST (MRA)
TREATMENT OF PATIENTS WITH CHRONIC KIDNEY DISEASE ASSOCIATED WITH TYPE 2 DIABETES

ORAL

Cmax 422.8 NANOMOLAR

Tmax 0.8 HOUR

F 44 PERCENT

VD 52.6 LITER

PPB 92 PERCENT

Cl 25 LITER / HOUR

HT 2.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

MINERALOCORTICOID RECEPTOR

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