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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M MOBOCERTINIB (is an active metabolite)

MOBOCERTINIB

ANTINEOPLASTIC
KINASE INHIBITOR
TREATMENT OF NSCLC WITH EGFR EXON 20 INSERTION MUTATIONS

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PPB 99.5 PERCENT

Cl 149 LITER / HOUR

HT 24 HOUR

EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) (MUTATED)

More at DrugCentralANSM (in French)

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ChEMBL
BindingDB
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