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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M ABROCITINIB (is an active metabolite)

ABROCITINIB


ATC D11AH08

DERMATOLOGICALS
TREATMENT OF ATOPIC DERMATITIS
JANUS KINASE 1 (JAK1) INHIBITOR

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PPB 29 PERCENT

HT 4 HOUR

JAK1 KINASE

Tyrosine-protein kinase JAK1 UNIPROT P23458

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