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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| IBREXAFUNGERP
| IBREXAFUNGERP | ANTIINFECTIVES | ORAL | Cmax 861 NANOMOLAR Tmax 5 HOUR VD 600 LITER PPB 99 PERCENT HT 20 HOUR | GLUCAN SYNTHASE | Beta-1,3-glucan synthase catalytic subunit 1 UNIPROT O13428 GSC1 -- 1,3-Beta-D-glucan-UDP glucosyltransferase UNIPROT Q6FTN8 FKS1 more at DrugCentral | EMA | |||
