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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VERICIGUAT
| VERICIGUAT | CARDIOVASCULAR | ORAL | Cmax 820.2 NANOMOLAR Tmax 1 HOUR F 93 PERCENT VD 44 LITER PPB 98 PERCENT Cl 1.6 LITER / HOUR HT 30 HOUR | Guanylate cyclase soluble subunit beta-1 UNIPROT Q02153 GUCY1B3 more at DrugCentral | EMA | ||||
