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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRILACICLIB
| TRILACICLIB | ANTINEOPLASTIC | INTRAVENOUS | VD 1130 LITER Cl 158 LITER / HOUR HT 14 HOUR | CDK4 CDK6 | Cyclin-dependent kinase 6 UNIPROT Q00534 CDK6 -- Cyclin-dependent kinase 4 UNIPROT P11802 CDK4 more at DrugCentral | EMA | |||
