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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TOLBUTAMIDE DISCONTINUED

TOLBUTAMIDE


ATC A10BB03
ATC V04CA01

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
SULFONYLUREAS
CHANNEL BLOCKER

ORAL INJECTION

Cmax 217.7 MICROMOLAR

Tmax 3.8 HOUR

VD 7.8 LITER (65 KILOGRAM)

PPB 95 PERCENT

Cl 0.819 LITER / HOUR (65 KILOGRAM)

HT 7 HOUR

K(ATP) CHANNEL

SULFONYLUREA RECEPTOR 1, Q09428 ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 HOMO SAPIENS TRANSPORTER NTPASE ATP BINDING CASSETTE MRPANSM (in French)

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