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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CAPMATINIB
| CAPMATINIB | ANTINEOPLASTIC | ORAL | Tmax 1.5 HOUR F 70 PERCENT VD 164 LITER PPB 96 PERCENT Cl 24 LITER / HOUR HT 6.5 HOUR SOLUBILITY LOW SOLUBILITY IN WATER | MET | Hepatocyte growth factor receptor UNIPROT P08581 MET more at DrugCentral | EMA | |||
