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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TUCATINIB

TUCATINIB


ATC L01EH03

ANTINEOPLASTIC
A TYROSINE KINASE INHIBITOR OF HER2
TREATMENT OF BREAST CANCER

ORAL

Tmax 2 HOUR

VD 1670 LITER

PPB 97.1 PERCENT

Cl 148 LITER / HOUR

HT 8.5 HOUR

HER2

ERBB2 INHIBITOR P04626 (ERBB2_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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