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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VOXELOTOR
| VOXELOTOR | BLOOD | ORAL | Cmax 11.3 MILLIMOLAR Tmax 2 HOUR VD 338 LITER PPB 99.8 PERCENT Cl 6.7 LITER / HOUR HT 35.5 HOUR SOLUBILITY INSOLUBLE IN WATER (APPROXIMATELY 0.03 MILLIGRAM PER MILLILITER) | HEMOGLOBIN (HBS) | hemoglobin subunit alpha UNIPROT P69905 HBA1 more at DrugCentral | EMA | |||
