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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CENOBAMATE

CENOBAMATE


ATC N03AX25

NERVOUS SYSTEM
TREATMENT OF PARTIAL-ONSET SEIZURES
INHIBITS VOLTAGE-GATED SODIUM CURRENTS
POSITIVE ALLOSTERIC MODULATOR OF THE GAMMA-AMINOBUTYRIC ACID (GABAA) ION CHANNEL

ORAL

Tmax 2.5 HOUR

F 88 PERCENT

VD 45 LITER

PPB 60 PERCENT

Cl 0.54 LITER / HOUR

HT 55 HOUR

SOLUBILITY VERY SOLUBLE IN AQUEOUS SOLUTIONS (1.7 MILLIGRAM PER MILLILITER)

Unknown - more at DrugCentralANSM (in French)

Dailymed
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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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