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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
RIMEGEPANT

RIMEGEPANT


ATC N02CD06

NERVOUS SYSTEM
TREATMENT OF MIGRAINE WITH OR WITHOUT AURA
A CALCITONIN GENE-RELATED PEPTIDE RECEPTOR ANTAGONIST

ORAL

Tmax 1.5 HOUR

F 64 PERCENT

VD 120 LITER

PPB 96 PERCENT

HT 11 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

CALCITONIN GENE-RELATED PEPTIDE RECEPTOR

Calcitonin gene-related peptide type 1 receptor antagonist Q16602 (CALRL_HUMAN)ANSM (in French)

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