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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CEDAZURIDINE

CEDAZURIDINE

ANTINEOPLASTIC
A CYTIDINE DEAMINASE (CDA) INHIBITOR
TREATMENT OF MYELODYSPLASTIC SYNDROMES (MDS)

ORAL

Cmax 1.39 MICROMOLAR

Tmax 3 HOUR

F 20 PERCENT

VD 296 LITER

PPB 64 PERCENT

Cl 30.3 LITER / HOUR

HT 6.7 HOUR

CYTIDINE DEAMINASE (CDA)

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