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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OPICAPONE
| OPICAPONE | NERVOUS SYSTEM | ORAL | Tmax 2 HOUR PPB 99 PERCENT HT 1.5 HOUR SOLUBILITY LIMITED AQUEOUS SOLUBILITY | CATECHOL-O-METHYLTRANSFERASE (COMT) | Catechol O-methyltransferase inhibitor P21964 (COMT_HUMAN) | ANSM (in French) | |||
